Jay-Z 'cheating' on Beyonce with Rita Ora? Calvin Harris' girlfriend denies BOGUS affair rumors, 'Don't disrespect Bey!' [VIDEO]

Rumors currently suggest that Beyonce and Jay-Z's marriage is falling apart. Despite such crazy gossip, HOV is NOT cheating on his "Bow Down" muse with fellow songstress, Rita Ora!

Not sure how this "romantic affair" all started, but apparently Jay is "sleeping around" with his much younger Roc-A-Fella Records protege.

But according to 23-year-old Ora, that's pure nonsense.

In a recent interview with Power 105.1's "The Breakfast Club," Calvin Harris' girlfriend exclaims:

 "Don't you dare disrespect Beyonce like that ever again in your entire life! That's just straight up disrespect. You can't even go there... That's like not even a question."

You go, girl.

Such cheating rumors initially went viral last year - Ora was forced to debunk them then, too.

Check out the full interview below. The "How We Do" songstress also dishes on Rihanna comparisons, her highly-publicized breakup with Rob Kardashian, her "Fifty Shades of Grey" movie role, and the infamous "Love & Hip-Hop" sex tape starring Mimi Faust: